Rabbit Polyclonal Antibody to CRKL

Description
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Specification
Swissprot	P46109
WB Predicted band size	34 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human CRKL
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application
WB	1/500-1/2000
IHC	1/25-1/100
ELISA	1/2000-1/5000