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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HepG2 cells, K562 cells, Primary antibody: P11649(CDC27 Antibody) at dilution 1/750, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds

The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P11649(CDC27 Antibody) at dilution 1/40. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to CDC27

货号：
P11649
别名：
APC3; HNUC; NUC2; ANAPC3; CDC27Hs; D0S1430E; D17S978E
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P30260
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to CDC27

Description
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Description

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Specification
Aliases	APC3; HNUC; NUC2; ANAPC3; CDC27Hs; D0S1430E; D17S978E
Swissprot	P30260
WB Predicted band size	92 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human CDC27
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.