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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11581(SH2B2 Antibody) at dilution 1/15. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P11581(SH2B2 Antibody) at dilution 1/15. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to SH2B2

货号：
P11581
别名：
APS
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human, Rat
抗体类型：
Primary antibody
Swissprot：
O14492
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to SH2B2

Description
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Description

The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Specification
Aliases	APS
Swissprot	O14492
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Rat
Immunogen	Synthetic peptide of human SH2B2
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.