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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: K562 cells, hela cells, Primary antibody: P11111(GEMIN2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes

The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P11111(GEMIN2 Antibody) at dilution 1/40. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P11111(GEMIN2 Antibody) at dilution 1/40. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to GEMIN2

货号：
P11111
别名：
SIP1, SIP1-delta
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
O14893
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to GEMIN2

Description
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Description

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Specification
Aliases	SIP1, SIP1-delta
Swissprot	O14893
WB Predicted band size	32 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human GEMIN2
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.