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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07246(TNFRSF10C Antibody) at dilution 1/30. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07246(TNFRSF10C Antibody) at dilution 1/30. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to TNFRSF10C

货号：
P07246
别名：
LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O14798
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to TNFRSF10C

Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

Specification
Aliases	LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
Swissprot	O14798
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human TNFRSF10C
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.