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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: RAW264.7 cell lysate, Primary antibody: P05488(CHD3 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 10 minutes

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P05488(CHD3 Antibody) at dilution 1/50. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to CHD3

货号：
P05488
别名：
ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q12873
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to CHD3

Description
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Description

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Specification
Aliases	ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA
Swissprot	Q12873
WB Predicted band size	226 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human CHD3
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.