Rabbit Polyclonal Antibody to SIN3B

Description
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).

Specification
Swissprot	O75182
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human SIN3B
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application
IHC	1/25-1/100
ELISA	1/5000-1/10000