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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human liver tissue lysate, Primary antibody: P05284(SIGLEC8 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes

The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P05284(SIGLEC8 Antibody) at dilution 1/75. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P05284(SIGLEC8 Antibody) at dilution 1/75. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to SIGLEC8

货号：
P05284
别名：
SAF2; SIGLEC-8; SIGLEC8L
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9NYZ4
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to SIGLEC8

Description
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM, and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein.

Description

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM, and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein.

Specification
Aliases	SAF2; SIGLEC-8; SIGLEC8L
Swissprot	Q9NYZ4
WB Predicted band size	54 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human SIGLEC8
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.