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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse thymus tissue, Primary antibody: P05098(TNFRSF13C Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P05098(TNFRSF13C Antibody) at dilution 1/45. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P05098(TNFRSF13C Antibody) at dilution 1/45. (Original magnification: ×200)
HOT

Rabbit Polyclonal Antibody to TNFRSF13C

  • 货号:

    P05098
  • 别名:

    BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human, Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q96RJ3
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to TNFRSF13C

Description

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Specification

Aliases BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Swissprot Q96RJ3
WB Predicted band size 19 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human TNFRSF13C
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/200-1/1000
IHC 1/50-1/200
ELISA 1/1000-1/2000