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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: P04841(EID3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P04841(EID3 Antibody) at dilution 1/15. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P04841(EID3 Antibody) at dilution 1/15. (Original magnification: ×200)

Rabbit Polyclonal Antibody to EID3

货号：
P04841
别名：
NS4EB; NSE4B; NSMCE4B
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q8N140
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to EID3

Description
EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

Description

EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

Specification
Aliases	NS4EB; NSE4B; NSMCE4B
Swissprot	Q8N140
WB Predicted band size	38 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human EID3
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.