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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Human leiomyosarcoma tissue lysate, Primary antibody: P04364(MCAM Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 seconds

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P04364(MCAM Antibody) at dilution 1/40. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P04364(MCAM Antibody) at dilution 1/40. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to MCAM

货号：
P04364
别名：
CD146; MUC18; HEMCAM; METCAM; MelCAM
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P43121
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to MCAM

Description
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Description

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Specification
Aliases	CD146; MUC18; HEMCAM; METCAM; MelCAM
Swissprot	P43121
WB Predicted band size	72 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human MCAM
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.