Rabbit Polyclonal Antibody to DENND6A

Description
Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes.

Specification
Aliases	AFI1A; FAM116A
Swissprot	Q8IWF6
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human DENND6A
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application
IHC	1/100-1/200
ELISA	1/5000-1/10000