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Western blot analysis of Phospho-Rb (Ser780) in K562, C6 lysates using Phospho-Rb (Ser780) antibody.
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Rabbit Monoclonal Antibody to Phospho-Rb (Ser780)

  • 货号:

    P20146
  • 别名:

    RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P06400
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to Phospho-Rb (Ser780)

Description

Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.

Specification

Aliases RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Entrez GeneID 5925
Swissprot P06400
WB Predicted band size Calculated MW: 106 kDa; Observed MW: 110 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser780 of human Rb
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P20146