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| 产品规范 | |
|---|---|
| Type | In Vivo - Reseach Grade Antibody |
| Host | CHO cells |
| catalog# | B00071.m1DA |
| Application | ELISA, WB, Flow cytometry, IHC, ICC, animal model study |
| Aliases | programmed cell death protein 1, PD-1, CD279, cluster of differentiation 279, 29F.1A12 |
| Size/Concentration | 1mg/5mg/25mg |
| clone | 29F.1A12.1 |
| Isotype | Mouse IgG1 Kappa |
| Storage | Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | The original rat hybridoma (clone name: 29F.1A12) was generated by immunizing rats with the mouse PD-1 cDNA followed by the mouse PD-1-Ig fusion protein. |
| Formulation | PBS, pH 7.4 |
Description |
|---|
The rat anti-mouse PD-1 monoclonal antibody 29F.1A12 (rat IgG2a kappa) reacts with the mouse PD-1 protein (programmed death-1 or CD279) encoded by the mouse Pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 29F.1A12 monoclonal antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein. Our recombinant 29F.1A12 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD-1 monoclonal antibody (hybridoma clone name or number: 29F.1A12). |
Recombinant Anti-mouse PD-1 Mouse IgG1-D265A Kappa Monoclonal Antibody (Clone 29F.1A12.1) B00071.m1DA
规格：
- 1mg
- 5mg
- 25mg
数量：
-
+
说明书：
¥1300
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