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产品规范
Type In Vivo - Reseach Grade Antibody
Host CHO cells
catalog# B00060
Application Flow cytometry, animal model study
Aliases Proprotein Convertase Subtilisin/Kexin Type 9
Size/Concentration 1mg/5mg/20mg
Isotype Human IgG2 lambda
Storage Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Human PCSK9
Formulation PBS, pH 7.4

Description

What is evolocumab biosimilar research grade? Evolocumab (trade name Repatha) is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin–kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels by approximately 60%. The PCSK9 protein targets LDL receptors for degradation. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR, in turn preventing PCSK9-mediated LDLR degradation and permitting the LDLR to recycle back to the liver cell surface. By inhibiting the binding of PCSK9 to LDLR, evolocumab increases the number of LDLRs available to clear LDL from the blood, thereby lowering LDL-C levels. Evolocumab biosimilar uses the same protein sequences as the therapeutic antibody evolocumab.

Evolocumab Biosimilar, Human PCSK9 Monoclonal Antibody B00060

规格:

  • 1mg
  • 5mg
  • 20mg

数量:

-
+

说明书:

¥1300

¥1300
加入购物车
立即购买
Evolocumab Biosimilar, Human PCSK9 Monoclonal Antibody-远泰生物
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搜索 英文站
栏目

提醒成功

请输入手机号/邮箱号
请输入密码

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没有账号? 立即注册

搜索
产品规范
Type In Vivo - Reseach Grade Antibody
Host CHO cells
catalog# B00060
Application Flow cytometry, animal model study
Aliases Proprotein Convertase Subtilisin/Kexin Type 9
Size/Concentration 1mg/5mg/20mg
Isotype Human IgG2 lambda
Storage Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Human PCSK9
Formulation PBS, pH 7.4

Description

What is evolocumab biosimilar research grade? Evolocumab (trade name Repatha) is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin–kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels by approximately 60%. The PCSK9 protein targets LDL receptors for degradation. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR, in turn preventing PCSK9-mediated LDLR degradation and permitting the LDLR to recycle back to the liver cell surface. By inhibiting the binding of PCSK9 to LDLR, evolocumab increases the number of LDLRs available to clear LDL from the blood, thereby lowering LDL-C levels. Evolocumab biosimilar uses the same protein sequences as the therapeutic antibody evolocumab.

Evolocumab Biosimilar, Human PCSK9 Monoclonal Antibody B00060

规格:

  • 1mg
  • 5mg
  • 20mg

数量:

-
+

说明书:

¥1300

¥1300
加入购物车
立即购买