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产品规范
Type In Vivo - Reseach Grade Antibody
Host CHO cells
catalog# B00050
Application Flow cytometry, animal model study
Aliases Anti-KDR Human Monoclonal Antibody, Ramucirumab Research Grade, Ramucirumab RUO
Size/Concentration 1mg/5mg/20mg
Isotype Human IgG1 kappa
Storage Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Human VEGFR2
Formulation PBS, pH 7.4

Description

What is ramucirumab biosimilar research grade? Research grade Ramucirumab biosimilar uses the same protein sequences as the therapeutic antibody ramucirumab. Ramucirumab, a fully human IgG1 monoclonal antibody and a direct VEGFR2 antagonist, binds with high affinity to the extracellular domain of VEGFR2 and block the binding of natural VEGFR ligands (VEGF-A, VEGF-C and VEGF-D). These ligands are secreted by solid tumors to promote angiogenesis (formation of new blood vessels from pre-existing ones) and enhance tumor blood supply. Binding of ramucirumab to VEGFR2 leads to inhibition of VEGF-mediated tumor angiogenesis. Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase, CD309, cluster of differentiation 309, Flk1, Fetal Liver Kinase 1) is the human gene encoding vascular endothelial growth factor receptor 2 (VEGFR-2), which is a VEGF receptor. The Q472H germline KDR genetic variant affects VEGFR-2 phosphorylation and has been found to associate with microvessel density in NSCLC.

Ramucirumab Biosimilar, Human VEGFR2 Monoclonal Antibody B00050

规格:

  • 1mg
  • 5mg
  • 20mg

数量:

-
+

说明书:

¥1300

¥1300
加入购物车
立即购买
Ramucirumab Biosimilar, Human VEGFR2 Monoclonal Antibody-远泰生物
请登录
搜索 英文站
栏目

提醒成功

请输入手机号/邮箱号
请输入密码

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没有账号? 立即注册

搜索
产品规范
Type In Vivo - Reseach Grade Antibody
Host CHO cells
catalog# B00050
Application Flow cytometry, animal model study
Aliases Anti-KDR Human Monoclonal Antibody, Ramucirumab Research Grade, Ramucirumab RUO
Size/Concentration 1mg/5mg/20mg
Isotype Human IgG1 kappa
Storage Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Human VEGFR2
Formulation PBS, pH 7.4

Description

What is ramucirumab biosimilar research grade? Research grade Ramucirumab biosimilar uses the same protein sequences as the therapeutic antibody ramucirumab. Ramucirumab, a fully human IgG1 monoclonal antibody and a direct VEGFR2 antagonist, binds with high affinity to the extracellular domain of VEGFR2 and block the binding of natural VEGFR ligands (VEGF-A, VEGF-C and VEGF-D). These ligands are secreted by solid tumors to promote angiogenesis (formation of new blood vessels from pre-existing ones) and enhance tumor blood supply. Binding of ramucirumab to VEGFR2 leads to inhibition of VEGF-mediated tumor angiogenesis. Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase, CD309, cluster of differentiation 309, Flk1, Fetal Liver Kinase 1) is the human gene encoding vascular endothelial growth factor receptor 2 (VEGFR-2), which is a VEGF receptor. The Q472H germline KDR genetic variant affects VEGFR-2 phosphorylation and has been found to associate with microvessel density in NSCLC.

Ramucirumab Biosimilar, Human VEGFR2 Monoclonal Antibody B00050

规格:

  • 1mg
  • 5mg
  • 20mg

数量:

-
+

说明书:

¥1300

¥1300
加入购物车
立即购买