Rabbit Polyclonal Antibody to ELOVL4

Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development.Zhang K., Nat. Genet. 27:89-93(2001).Edwards A.O., Invest. Ophthalmol. Vis. Sci. 42:2652-2663(2001).Ota T., Nat. Genet. 36:40-45(2004).