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Rabbit Polyclonal Antibody to CTDSP1
Western blot analysis of extracts from HUVEC cells and HeLa cells, using CTDSP1 antibody P42334.
Rabbit Polyclonal Antibody to CTDSP1
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 antibody P42334.
Rabbit Polyclonal Antibody to CTDSP1
Rabbit Polyclonal Antibody to CTDSP1

Rabbit Polyclonal Antibody to CTDSP1

  • 货号:

    P42334
  • 别名:

    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; EC 3.1.3.16; Nuclear LIM interactor-interacting factor 3; NLI-interacting factor 3; NLI-IF
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9GZU7
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to CTDSP1

Description

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.Marquet S., Mamm. Genome 11:755-762(2000).Yeo M., J. Biol. Chem. 278:26078-26085(2003).Hillier L.W., Nature 434:724-731(2005)

Specification

Aliases Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; EC 3.1.3.16; Nuclear LIM interactor-interacting factor 3; NLI-interacting factor 3; NLI-IF
Entrez GeneID 58190;
Swissprot Q9GZU7
WB Predicted band size 30kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from N-terminal of human CTDSP1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42334