Rabbit Polyclonal Antibody to eNOS(Phospho-Ser1177)

Description
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

References
Fulton, D. et al. (1999) Nature 399, 597-601. Harris, M.B. et al. (2001) J. Biol. Chem. 276, 16587-16591. Thomas, S.R. et al. (2002) J. Biol. Chem. 277, 6017-6024.

Specification
Aliases	Constitutive NOS; EC-NOS; ECNOS; NOS3; NOSIII
Entrez GeneID	4846;
Swissprot	P29474
WB Predicted band size	133kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 1177 (T-Q-S(p)-F-S) derived from Human eNOS.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000