请登录
搜索 英文站
栏目

提醒成功

请输入手机号/邮箱号
请输入密码

账号密码登录

微信/QQ登录 微信/QQ登录

没有账号? 立即注册

搜索
Rabbit Monoclonal Antibody to DAB2
Western blot analysis of DAB2 in Hela, A549, HL-60, U2OS, C6 lysates using DAB2 antibody.
Rabbit Monoclonal Antibody to DAB2
Immunocytochemistry analysis of DAB2 (green) in hela using DAB2 antibody,and DAPI(blue)
Rabbit Monoclonal Antibody to DAB2
Rabbit Monoclonal Antibody to DAB2

Rabbit Monoclonal Antibody to DAB2

  • 货号:

    P22666
  • 别名:

    DOC2; DOC-2
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IF
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P98082
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

加入购物车

Rabbit Monoclonal Antibody to DAB2

Description

This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specification

Aliases DOC2; DOC-2
Entrez GeneID 1601
Swissprot P98082
WB Predicted band size Calculated MW: 82 kDa; Observed MW: 96 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen A synthetic peptide of human DAB2
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IF/ICC 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P22666