Mouse Monoclonal Antibody to KMT2D

Description
The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

References
1.Clin Lung Cancer. 2018 Jul;19(4):e489-e501. 2.J Cancer Res Clin Oncol. 2018 Jun;144(6):1025-1035.

Specification
Aliases	ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114
Entrez GeneID	8085
Swissprot	O14686
clone	1D10F6
WB Predicted band size	593kDa
Host/Isotype	Mouse IgG2b
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human KMT2D (AA: 445-599) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
IHC	1/200 - 1/1000
FCM	1/200 - 1/400
ELISA	1/10000