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Western blot analysis of Rad21 in Hela, CHO-K1, Ramos lysates using Rad21 antibody.

Immunocytochemistry analysis of Rad21 (green) in Hela using Rad21 antibody,and DAPI(blue).

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Rad21 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Rabbit Monoclonal Antibody to Rad21

货号：
P22549
别名：
RAD21; HR21; KIAA0078; NXP1; Double-strand-break repair protein rad21 homolog; hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Hamster
抗体类型：
Primary antibody
Swissprot：
O60216
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to Rad21

Description
Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.

Description

Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.

Specification
Aliases	RAD21; HR21; KIAA0078; NXP1; Double-strand-break repair protein rad21 homolog; hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog
Entrez GeneID	5885
Swissprot	O60216
WB Predicted band size	Calculated MW: 72 kDa; Observed MW: 130 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Hamster
Immunogen	A synthetic peptide of human Rad21
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.