Rabbit Monoclonal Antibody to HIF1AN

Description
Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator.

Specification
Aliases	FIH 1; FIH1; HIF1AN
Entrez GeneID	55662
Swissprot	Q9NWT6
WB Predicted band size	Calculated MW: 40 kDa; Observed MW: 40 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human HIF1AN/FIH-1
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100
IF/ICC	1/50-1/200