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Rabbit Monoclonal Antibody to HIF1 beta
Western blot analysis of HIF1 beta in Raw264.7, 3T3 lysates using HIF1 beta antibody.
Rabbit Monoclonal Antibody to HIF1 beta
Western blot analysis of HIF1 beta in Hela, CHO-K1, C6, Ramos lysates using HIF1 beta antibody.
Rabbit Monoclonal Antibody to HIF1 beta
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using HIF1 beta antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Rabbit Monoclonal Antibody to HIF1 beta
Rabbit Monoclonal Antibody to HIF1 beta
Rabbit Monoclonal Antibody to HIF1 beta

Rabbit Monoclonal Antibody to HIF1 beta

  • 货号:

    P22393
  • 别名:

    ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse,Rat,Hamster
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P27540
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to HIF1 beta

Description

HIF-1β is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1β plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1β expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1β plays an important role in pancreatic β-cell function.

Specification

Aliases ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
Entrez GeneID 405
Swissprot P27540
WB Predicted band size Calculated MW: 87 kDa; Observed MW: 87 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat,Hamster
Immunogen Recombinant protein of human HIF1 beta
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100