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Mouse Monoclonal Antibody to CD130
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Mouse Monoclonal Antibody to CD130
Western blot analysis using CD130 mouse mAb against COS7 (1) cell lysate.
Mouse Monoclonal Antibody to CD130
Immunofluorescence analysis of Hela cells using CD130 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Mouse Monoclonal Antibody to CD130
Flow cytometric analysis of HL-60 cells using CD130 mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to CD130
Mouse Monoclonal Antibody to CD130
Mouse Monoclonal Antibody to CD130
Mouse Monoclonal Antibody to CD130

Mouse Monoclonal Antibody to CD130

  • 货号:

    31686
  • 别名:

    IL6ST; GP130; CDW130; IL-6RB
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF,FCM
  • 反应种属:

    Human,Monkey
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P40189
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CD130

Description

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]

References

1.J Exp Med. 2017 Sep 4;214(9):2547-2562.
2.Biochem Biophys Res Commun. 2016 Feb 19;470(4):870-6.

Specification

Aliases IL6ST; GP130; CDW130; IL-6RB
Entrez GeneID 3572
Swissprot P40189
clone 8D4C5
WB Predicted band size 103.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Monkey
Immunogen Purified recombinant fragment of human CD130 (AA: extra 73-231) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IF/ICC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000