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Rabbit Monoclonal Antibody to U1C
Western blot analysis of U1C in rat lung lysates using U1C antibody.
Rabbit Monoclonal Antibody to U1C
Western blot analysis of U1C in THP-1, Jurkat, Hela, K562 lysates using U1C antibody.
Rabbit Monoclonal Antibody to U1C
Rabbit Monoclonal Antibody to U1C

Rabbit Monoclonal Antibody to U1C

  • 货号:

    P22141
  • 别名:

    U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IHC,IF
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P09234
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to U1C

Description

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.

Specification

Aliases U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C
Entrez GeneID 6631
Swissprot P09234
WB Predicted band size Calculated MW: 17 kDa; Observed MW: 21 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen A synthetic peptide of human U1-C
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
IF/ICC 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P22141