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Mouse Monoclonal Antibody to PI3 Kinase p85 alpha
Western blot analysis of PI3 Kinase p85 alpha in Jurkat, rat Brain, Raw264.7, Ramos, Raji lysates using PI3 Kinase p85 alpha antibody
Mouse Monoclonal Antibody to PI3 Kinase p85 alpha
Western blot analysis of PI3 Kinase p85 alpha in Hela, A549, HL-60, U2OS, C6 lysates using PI3 Kinase p85 alpha antibody.
Mouse Monoclonal Antibody to PI3 Kinase p85 alpha
Immunohistochemistry analysis of paraffin-embedded rat Liver Tissue using PI3 Kinase p85 alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Mouse Monoclonal Antibody to PI3 Kinase p85 alpha
Immunohistochemical analysis of paraffin-embedded Human tonsils using PI3 Kinase p85 alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Mouse Monoclonal Antibody to PI3 Kinase p85 alpha
Mouse Monoclonal Antibody to PI3 Kinase p85 alpha
Mouse Monoclonal Antibody to PI3 Kinase p85 alpha
Mouse Monoclonal Antibody to PI3 Kinase p85 alpha

Mouse Monoclonal Antibody to PI3 Kinase p85 alpha

  • 货号:

    P20782
  • 别名:

    PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P27986
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to PI3 Kinase p85 alpha

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Specification

Aliases PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Entrez GeneID 5295
Swissprot P27986
clone 1C8
WB Predicted band size Calculated MW: 84 kDa; Observed MW: 84 kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Purified recombinant protein expressed in E.coli.
Formulation Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100