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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Immunofluorescence analysis of Hela cells using MR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Flow cytometric analysis of Jurkat cells using MR1 mouse mAb (green) and negative control (red).
Flow cytometric analysis of THP-1 cells using MR1 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using MR1 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to MR1

  • 货号:

    32051
  • 别名:

    HLALS
  • 应用:

    IHC,ICC,FCM
  • 反应种属:

    Human
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to MR1

Description

MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

References
1,J Immunol. 2019 Dec 1;203(11):2917-2927.
2,Science. 2019 Dec 20;366(6472):1522-1527.
Specification
Aliases HLALS
Entrez GeneID 3140
Swissprot Q95460
clone 6A5B2
WB Predicted band size 39.4kDa
Host/Isotype Mouse IgG2a
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human MR1 (AA: extra(23-302)) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
IHC 1/200 - 1/1000
ICC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000