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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using IGF1R mouse mAb against NIH3T3 (1), cell lysate.
Flow cytometric analysis of HepG2 cells using IGF1R mouse mAb (green) and negative control (red).
Flow cytometric analysis of Lovo cells using IGF1R mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to IGF1R

  • 货号:

    32052
  • 别名:

    IGFR; CD221; IGFIR; JTK13
  • 应用:

    WB,FCM
  • 反应种属:

    Human
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to IGF1R

Description

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

References
1,Cells. 2019 Dec 14;8(12):1638.
2,Nature. 2020 Jul;583(7817):615-619.
Specification
Aliases IGFR; CD221; IGFIR; JTK13
Entrez GeneID 3480
Swissprot P08069
clone 3B4E3
WB Predicted band size 154.8kDa
Host/Isotype Mouse IgG2a
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000