Description

This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.

References
1. Biochem Biophys Res Commun. 2004 Jul 16;320(1):1-6. 2. Front Biosci. 2004 Sep 1;9:2388-413.

Specification
Aliases	TF2B; TFIIB; GTF2B
Entrez GeneID	2959
Swissprot	Q00403
clone	4C1
WB Predicted band size	34.8kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Monkey
Immunogen	Purified recombinant fragment of human GTF2B expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Application
WB	1/500 - 1/2000
ELISA	1/10000