Description

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

References
Anticancer Res. 2011 Jan;31(1):77-9. J Invest Dermatol. 2012 Nov;132(11):2632-41.

Specification
Aliases	TIP; ESA1; PLIP; KAT5; cPLA2; HTATIP; ZC2HC5; HTATIP1
Entrez GeneID	10524
Swissprot	Q92993
clone	2A11H7
WB Predicted band size	58.6kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human TIP60 (AA: 18-208) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500 - 1/2000
FCM	1/200 - 1/400
ELISA	1/10000