Description

TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

References
1. Blood. 2000 Nov 15;96(10):3406-13. 2. J Biol Chem. 1999 Jan 8;274(2):607-17. 3. Blood. 1998 Feb 1;91(3):940-8.

Specification
Aliases	PSCTK4
Entrez GeneID	7006
Swissprot	P42680
clone	3A5
WB Predicted band size	74kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of TEC expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Application
ELISA	1/10000