Description
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found.

References
1.Alcohol Clin Exp Res. 2015 Jun;39(6):962-8. 2.J Biol Chem. 2012 Nov 23;287(48):40713-21.

Specification
Aliases	STHE; HKPX1
Entrez GeneID	2741
Swissprot	P23415
clone	7F8E2
WB Predicted band size	52.6kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human GLRA1 (AA: extra 29-154) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
ELISA	1/10000